Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00851 |
IDE Protein, Human, Recombinant (His)
Insulysin,Insulinase,Insulin-Degrading Enzyme,IDE,A... |
Human | HEK293 Cells |
Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted... |